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Wissenschaftliche Projekte

NamePHILOS (Fracture fixation in osteoporotic bone / proximal humerus)
Study TypeObservational prospective multicenter open cohort study
QuestionThe primary aim of this study is to evaluate if poor bone quality (determined by local Bone Mineral Density (BMD) increases the risk of specific types of treatment complications in patients with proximal humerus fractures treated with open reduction and angle stable plates (Proximal Humeral Internal Locking System (PHILOS).
Investigational SitesSites in Switzerland, Germany, Austria and Hong Kong
CollaborationAO Foundation


Name5th anchoring point
Study TypeBiomechanical study
QuestionVarus failure is one of the most common failure modes following surgical treatment of proximal humeral fractures. Besides proximal and distal locking screws, straight antegrade nails (SAN) are supposed to be additionally anchoring in the proximal humeral cortex with the proximal nail's end. The aim of this biomechanical study was to investigate the characteristics of this "5th anchoring point". We hypothesized that the additional anchoring point would improve stability compared to the same construct without the 5th anchoring point.
Investigational SitesInnsbruck, Austria; Vail, Colorado, USA
CollaborationDePuy Synthes; Steadman-Phillipon Research Institute Vail, Colorado, USA


NameProximal nail entry point
Study TypeDescriptive anatomical study
QuestionComparison of the ideal straight antegrade humeral nail's entrypoint on the humeral head, using 40 cadaveric humeri. Entrypoints will be determined using CT scans in the first step, and by "ideal" implantation of the physical nails into the real specimens.
Investigational SitesInnsbruck, Austria; Vail, Colorado, USA
CollaborationDePuy Synthes; Steadman-Phillipon Research Institute Vail, Colorado, USA


NameAllografting proximal humerus
Study Typeretrospective clinical study
QuestionTo augment the surgical fixation and to achieve postoperative stability strong enough to initially start full range of movement and to prevent secondary displacement in unstable fracture patterns and/or weak and osteoporotic bone. A bony allograft will be used. Long term clinical and radiological outcomes will be observed.
Investigational SitesInnsbruck, Austria


NameMassive Rotator cuff tears
Study Typereview paper (german)
QuestionZusammenfassung aller relevanten Techniken und deren Bewertung sowie Vorschlag eines möglichen Algorithmus zur Behandlung großer und massiver Rumturne der Rotatorenmanschette.
Investigational SitesInnsbruck, Austria; Vail, Colorado, USA
CollaborationSteadman Clinic and Steadman-Phillipon Research Institute Vail, Colorado, USA


NameTotal shoulder arthroplasty
Study Typeretrospective clinical study
QuestionThe use of total shoulder arthroplasty (TSA) to treat primary glenohumeral osteoarthritis (GHOA) is increasing. Factors influencing patient satisfaction after surgery have not been well documented. The aim of this study was to determine demographic, radiologic and surgical factors predictive for satisfaction after TSA for GHOA.
Investigational SitesInnsbruck, Austria; Vail, Colorado, USA
CollaborationSteadman Clinic and Steadman-Phillipon Research Institute Vail, Colorado, USA


NameDouble row vs. single row rotator cuff repair
Study Typereview paper
QuestionMetaanalysis fto find potential evidence of the clinical superiority of one over the other surgical technique
Investigational SitesInnsbruck, Austria; Leipzig, Germany; Hannover, Germany; Vail, Colorado, USA
CollaborationSteadman Clinic and Steadman-Phillipon Research Institute Vail, Colorado, USA; University of Hannover, Germany; University of Leipzig, Germany


NameAutopsy
Study Typeretrospective clinical study
QuestionIn spite of increasing quality of emergency room (ER) assessment in trauma patients and improved accuracy of modern multislice computed tomography (MSCT), the number of potentially missed diagnoses is still controversial. The aim of this study was to compare the initial findings of ER assessment and MSCT to the findings in autopsy in trauma patients not surviving the first 48 hours after admission. We hypothesized that autopsy was more accurate than MSCT in diagnosing potentially fatal diagnoses. 
Investigational SitesInnsbruck, Austria
CollaborationUniversity of Hannover, Germany